Gomariz et al., J Leukoc Biol 2005
(Autoimmune Diseases...) :
Vasoactive intestinal peptide (VIP) treatment induced a decrease of TLR2 and -4 expressions approaching ethanol control levels
Gutiérrez-Cañas et al., Rheumatology (Oxford) 2006
(Arthritis, Rheumatoid...) :
The effects of VIP on basal or TNF-alpha or lipopolysaccharide (LPS) induced TLR2 , TLR4 and MyD88 expression and its effects on TLR4 mediated CCL2 and CXCL8 chemokine production were studied by reverse transcription-polymerase chain reaction, western blotting and enzyme linked immunosorbent assay
Arranz et al., Ann N Y Acad Sci 2006
(Colitis...) :
Effect of VIP on TLR2 and TLR4 expression in lymph node immune cells during TNBS induced colitis
Foster et al., J Leukoc Biol 2007
:
Pivotal advance : vasoactive intestinal peptide inhibits up-regulation of human monocyte TLR2 and TLR4 by LPS and differentiation of monocytes to macrophages ... VIP decreased monocyte differentiation to macrophages induced by LPS from either species and also reduced overall TLR2 and TLR4 expression in these cells
Zuo et al., Zhonghua Er Ke Za Zhi 2010
(Acute Lung Injury) :
The present study was conducted to investigate the effects of VIP on TLR2/4 mRNA expressions on acute lung injury of endotoxic shock induced by lipopolysaccharide (LPS) in rat