◀ Back to VIP

IL1B — VIP

Text-mined interactions from Literome

Delgado et al., J Leukoc Biol 2003 : VIP and PACAP inhibit TNF-alpha, IL-1beta , IL-6, and NO production by lipopolysaccharide (LPS) activated microglia
Hernanz et al., Regul Pept 2003 (Arthritis, Rheumatoid...) : In the present study, we have investigated the in vitro effect of calcitonin related peptide ( CGRP ), neuropeptide Y (NPY), substance P ( SP ) and vasoactive intestinal peptide (VIP) at concentrations of 10 ( -8 ), 10 ( -9 ) and 10 ( -10 ) M on the production of different proinflammatory cytokines or chemokines such as IL-1beta , IL-6 and TNFalpha by peripheral whole blood cells from patients with rheumatoid arthritis, as well as from osteoarthritis patients studied as a control group without immunoinflammatory background
Foster et al., J Interferon Cytokine Res 2005 : We report that VIP inhibited production of the proinflammatory cytokines, tumor necrosis factor-alpha(TNF-alpha)and interleukin-1beta (IL-1beta) , at the mRNA level and that the inhibitory effect of VIP was maintained when macrophages were cocultured with an immunostimulatory concentration of interferon-gamma (IFN-gamma) ( 100 U/ml )
Persson et al., Biochem Biophys Res Commun 2005 : Furthermore, IL-1beta stimulated IL-6 promoter activity in the osteoblastic cell line MC3T3-E1 stably transfected with a human IL-6 promoter/luciferase construct, and both VIP , and the related neuropeptide PACAP-38, increased the effect of IL-1beta in a synergistic manner
Kelleher et al., J Immunol 1991 : Our results demonstrated that vasoactive intestinal peptide , the beta-adrenergic agonist, isoproterenol, PGE2, IL-1 alpha, IL-1 beta , and TNF-alpha significantly increased media SC levels in control or androgen containing cell cultures
Favrais et al., Peptides 2007 (Inflammation) : Therefore, we first tested the effects of peripheral IL-1beta on VIP and PACAP central production
Spangelo et al., Endocrinology 1991 : In the presence of VIP and PGE2, IL-1 alpha and IL-1 beta increased IL-6 release without any apparent further change in extracellular or intracellular cAMP
Brenneman et al., Int J Dev Neurosci 1995 : Interleukin-1 beta (IL-1 beta) was also increased ( EC 50 : 1 nM ) in the medium by VIP but without depleting IL-1 beta in the cytosol
Hernanz et al., J Neuroimmunol 1996 : Differential effects of gastrin releasing peptide, neuropeptide Y, somatostatin and vasoactive intestinal peptide on interleukin-1 beta , interleukin-6 and tumor necrosis factor-alpha production by whole blood cells from healthy young and old subjects ... We have found that GRP, NPY, somatostatin and VIP stimulated the production of IL-1 beta in old subjects, and NPY, somatostatin and VIP in young ones ... In the present study, we have investigated the effect in vitro of gastrin releasing peptide ( GRP, 10 ( -10 ) M ), neuropeptide Y ( NPY, 10 ( -10 ) M ), somatostatin ( 10 ( -10 ) M ) and vasoactive intestinal peptide ( VIP, 10 ( -9 ) M ) on the production of IL-1 beta , IL-6 and TNF alpha by peripheral whole blood cells from healthy young and old people