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TCF19 — VEGFA

Text-mined interactions from Literome

Vincent et al., Circulation 2000 (Ischemia) : After transfection into HeLa, C6, and Hep3B cells, this chimeric transcription factor was shown to activate expression of the endogenous VEGF gene, as well as several other HIF-1 target genes in vitro
Mayo et al., J Biol Chem 2001 : Binding of VEGF to the KDR/Flk1 receptor tyrosine kinase induces phosphorylation of the CRE binding protein ( CREB ) transcription factor on serine 133 and increases CREB DNA binding and transactivation
Hu et al., Zhonghua Yi Xue Za Zhi 2001 : Triptolide might inhibit VEGF expression and production by interfering with transcription factor AP-1 formation
Bartoli et al., FASEB J 2003 : Previous studies have shown that the transcription factor STAT3 mediates VEGF gene transcription and its activation
Na et al., J Urol 2003 (Carcinoma, Renal Cell...) : The VHL protein targets hypoxia-inducible factor-1 alpha ( HIF-1 alpha ), a transcription factor that can induce vascular endothelial growth factor ( VEGF ) expression, for ubiquitination and degradation
Kirito et al., Cell cycle (Georgetown, Tex.) 2005 : Like several other effects of the cytokine, the effect of TPO on VEGF expression is mediated by stabilization and activation of the primary transcription factor responsible for VEGF expression, the oxygen tension responsive hypoxia inducible factor-1 (HIF-1)
Du et al., Ophthalmic Res 2007 (Diabetes Mellitus, Experimental) : To investigate the role played by E26 transformation-specific-1 (Ets-1), a transcription factor , and extracellular signal regulated kinase 1/2 ( ERK1/2 ) in the expression of vascular endothelial growth factor ( VEGF ), and the interaction of Ets-1 and ERK1/2 in the retina of diabetic rats
Garcia et al., Exp Eye Res 2009 (Cataract) : The lens is hypoxic throughout most of life and VEGF-A expression is often regulated by the transcription factor , hypoxia inducible factor-1
Sakowski et al., Gene Ther 2009 (Recurrent Laryngeal Nerve Injuries...) : Overall, adenoviral delivery of an engineered ZFP transcription factor inducing VEGF-A splice variant expression enhances nerve regeneration
Hutson et al., J Clin Oncol 2010 (Carcinoma, Renal Cell...) : Inactivation of the von Hippel-Lindau gene in clear-cell renal cell carcinomas (RCC) leads to overexpression of hypoxia inducible factor, a transcription factor regulating vascular endothelial growth factor ( VEGF ) and platelet derived growth factor ( PDGF ) gene expression
Cao et al., Oncogene 2012 (Breast Neoplasms...) : Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells
Rohr-Udilova et al., Hepatology 2012 (Carcinoma, Hepatocellular...) : Activation of the activator protein 1 (AP-1) transcription factor as well as increased serum levels of vascular endothelial growth factor ( VEGF ) and interleukin (IL)-8 predict poor prognosis of patients with hepatocellular carcinomas (HCCs)
Kaga et al., Vascul Pharmacol 2012 (Inflammation) : In addition, bFGF, but not HGF or VEGF , significantly activated an essential transcription factor for inflammation, NF?B, and gene expression of its downstream inflammation related cytokines ( IL-8 and MCP-1 ) in VSMCs, accompanied by an increase in the vascular permeability in the rat paper disc model
Albasanz-Puig et al., Biochem Biophys Res Commun 2012 : Using shRNA and overexpression studies, we have shown that the transcription factor , STAT-1 inhibited VEGF expression, while STAT-3 promoted the expression of VEGF
Finkenzeller et al., Biochem Biophys Res Commun 1995 : Hypoxia induced transcription of the vascular endothelial growth factor gene is independent of functional AP-1 transcription factor