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RB1 — VEGFA

Text-mined interactions from Literome

Kimura et al., Br J Pharmacol 2006 (Burns) : Furthermore, ginsenoside Rb1 ( 100 fg-1 ng per wound ) increased neovascularization in the surrounding tissue and production of vascular endothelial growth factor ( VEGF ) and interleukin (IL)-1beta from the burn wound, compared to those mice with burn wounds treated with vehicle alone ... 3. In human keratinocyte cultures ( HaCaT cells ), ginsenoside Rb1 ( 100 fg ml(-1) to 1 ng ml(-1) ) enhanced VEGF production induced by IL-1beta and expression of hypoxia-inducible factor (HIF)-1alpha
Gao et al., Cancer Biother Radiopharm 2009 (Bone Neoplasms...) : The study demonstrates potent growth and pulmonary metastasis inhibitory effects of VEGF-siRNA on osteosarcoma in vivo and in vitro, which could potentially be applicable to the treatment of cancers as an antiangiogenic therapeutic in the near future