◀ Back to VEGFA

CXCL12 — VEGFA

Text-mined interactions from Literome

Darash-Yahana et al., FASEB J 2004 (Adenocarcinoma...) : In vitro, CXCL12 induced the proliferation and VEGF secretion but not migration of PC3 and 22Rv1 cells overexpressing CXCR4
Hosokawa et al., Clin Exp Immunol 2005 (Periodontal Diseases) : Moreover, CXCL12 induced vascular endothelial growth factor ( VEGF ) production by HGF
Brand et al., Exp Cell Res 2005 (Colorectal Neoplasms...) : Moreover, CXCL12 increases vascular endothelial growth factor ( VEGF ) expression and cell proliferation but has no effect on CRC apoptosis ... Moreover, CXCL12 increases vascular endothelial growth factor ( VEGF ) expression and cell proliferation but has no effect on CRC apoptosis
Wang et al., Heart 2006 (Myocardial Infarction...) : Plasma SDF-1 increased significantly from day 3 to day 28, and VEGF-A and FGF-2 increased significantly from day 7 to day 28
Yao et al., J Neurooncol 2008 (Disease Models, Animal...) : In this study, we examined the capacity of FPR to regulate the production of another angiogenic factor, the chemokine IL-8 ( CXCL8 ), in addition to its demonstrated ability to induce VEGF secretion by malignant glioma cells
Bian et al., Neurosurgery 2007 (Brain Neoplasms...) : Tumor cell chemotaxis and production of vascular endothelial growth factor induced by the CXCR4 ligand SDF-1beta were measured
Zagzag et al., Am J Pathol 2008 (Brain Neoplasms...) : Hypoxia- and vascular endothelial growth factor induced stromal cell derived factor-1alpha/CXCR4 expression in glioblastomas : one plausible explanation of Scherer 's structures
Martin et al., J Biol Chem 2009 : CXCL8/IL8 stimulates vascular endothelial growth factor ( VEGF ) expression and the autocrine activation of VEGFR2 in endothelial cells by activating NFkappaB through the CBM ( Carma3/Bcl10/Malt1 ) complex ... Furthermore, we identified the components of the CBM complex, Carma3, Bcl10, and Malt1, as key mediators of the CXCL8/IL8 induced NFkappaB activation and VEGF up-regulation ... Together, these findings support the existence of an NFkappaB mediated pathway by which the proinflammatory chemokine CXCL8/IL8 controls the expression of VEGF in endothelial cells, thereby promoting the activation of VEGF receptors in an autocrine fashion
Unoki et al., Invest Ophthalmol Vis Sci 2010 (Retinal Neovascularization) : In ex vivo experiments, VEGF induced SDF-1 mRNA expression, and the inhibition of SDF-1/CXCR4 decreased the number of VEGF induced neovascular sprouts