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TPM1 — TPM2
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Biogrid Interaction:
TPM2
—
TPM1
(direct interaction, pull down)
Brown et al., Proc Natl Acad Sci U S A 1985*
-
IRef Biogrid Interaction:
TPM2
—
TPM1
(colocalization, biochemical)
Havugimana et al., Cell 2012
-
IRef Hprd Interaction:
TPM1
—
TPM2
(in vitro)
Brown et al., Proc Natl Acad Sci U S A 1985*, Gimona et al., Proc Natl Acad Sci U S A 1995*
-
IRef Hprd Interaction:
TPM1
—
TPM2
(in vivo)
Brown et al., Proc Natl Acad Sci U S A 1985*, Gimona et al., Proc Natl Acad Sci U S A 1995*
-
IRef Intact Interaction:
Complex of 23 proteins
(physical association, tandem affinity purification)
Hutchins et al., Science 2010
-
IRef Intact Interaction:
Complex of 228 proteins
(association, pull down)
Blagoev et al., Nat Biotechnol 2003
-
IRef Intact Interaction:
Complex of TPM1-RAI14-TPM2
(physical association, tandem affinity purification)
Hutchins et al., Science 2010
Text-mined interactions from Literome
Prabhakar et al., J Mol Cell Cardiol 2001
(Cardiomyopathy, Hypertrophic, Familial) :
Expression of exogenous mutant
tropomyosin leads to a concomitant decrease in endogenous
alpha-tropomyosin without altering the expression of other contractile proteins
Varga et al., Oncogene 2005
(Breast Neoplasms...) :
Treatment of these cells with demethylating agent 5-aza-2'-deoxycytidine ( 5-aza-dC )
increased mRNA levels of
TPM1 with no effect on
TPM2