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GSN — TPM1
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Ciesielski-Treska et al., Eur J Cell Biol 1991
:
Since
tropomyosin stabilizes microfilaments and
inhibits the severing activity of
gelsolin , the toxin induced phosphorylation may counteract this inhibition resulting in severing of microfilaments and capping of short filaments
Khaitlina et al., FEBS J 2013
:
Under nonpolymerizing conditions, binding of
tropomyosin neither
prevented the formation of a 2 : 1 actin-gelsolin complex, nor did it affect the nucleating activity of
gelsolin in actin polymerization, likely as a result of competitive displacement of tropomyosin from gelsolin ... To evaluate the
effect of
tropomyosin on the actin filament severing activity of
gelsolin , we measured both filamentous actin ( F-actin ) viscosity and the relative number concentrations of filaments after fragmentation, either by gelsolin alone or by gelsolin-tropomyosin complexes