◀ Back to TP53

RPL11 — TP53

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: TP53 — RPL11 (physical association, affinity chromatography technology) Bursać et al., Proc Natl Acad Sci U S A 2012
• IRef Biogrid Interaction: TP53 — RPL11 (physical association, affinity chromatography technology) Zhang et al., Mol Cell Biol 2003
• IRef Biogrid Interaction: TP53 — RPL11 (physical association, affinity chromatography technology) Dai et al., J Biol Chem 2004

Text-mined interactions from Literome

Bhat et al., EMBO J 2004 : Essential role of ribosomal protein L11 in mediating growth inhibition induced p53 activation
Hölzel et al., J Biol Chem 2010 : Interestingly, accumulation of p53 after hUTP18 knock down required the ribosomal protein L11
Lindström et al., PloS one 2010 (Brain Neoplasms...) : In these settings, RPL11 was critical for maintaining p53 protein stability but was not strictly required for p53 protein synthesis
Sun et al., J Biol Chem 2010 : Perturbation of 60 S ribosomal biogenesis results in ribosomal protein L5- and L11 dependent p53 activation
Zhang et al., J Biol Chem 2011 : Ribosomal protein L11 (RPL11) has been shown to activate p53 by binding to MDM2 and negating its p53 suppression activity in response to ribosomal stress
Golomb et al., Mol Cell 2012 : Furthermore, p53 activation is dependent on RPL5 and RPL11
Dai et al., J Biol Chem 2012 : The ARF tumor suppressor protein activates p53 in response to oncogenic stress, whereas ribosomal protein L11 induces p53 following ribosomal stress