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CALML3 — TNF
Text-mined interactions from Literome
Huynh et al., Shock 2000
(Femoral Fractures...) :
By contrast,
CLP and FFx + CLP
increased TNF-alpha release 25 % and 100 %, respectively
Song et al., Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 2004
(Disease Models, Animal...) :
CLP produced progressive hypotension, and a large
increase in the plasma
TNF-alpha and IL-6 concentrations
Dal-Pizzol et al., Am J Respir Crit Care Med 2006
(Disease Models, Animal...) :
The GRP antagonist attenuated LPS- or
CLP induced
TNF-alpha , IL-1beta, and nitric oxide release in cultured macrophages and decreased the mRNA levels of inducible nitric oxide synthase
Xi et al., Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 2006
(Disease Models, Animal...) :
To evaluate the
changes in
tumor necrosis factor-alpha (TNF-alpha) mRNA expression in peripheral polymorphonuclear leukocyte ( PMNs ) and tissues after
cecal ligation puncture (CLP) in rats
Yasuda et al., Kidney Int 2006
(Acute Kidney Injury...) :
Simvastatin attenuated CLP induced tubular damage and reversed CLP induced reduction of intrarenal microvascular perfusion and renal tubular hypoxia at 24 h. Simvastatin also restored towards normal
CLP induced renal vascular protein leak and serum
TNF-alpha
Anuar et al., Inflamm Res 2006
(Disease Models, Animal...) :
CLP ( 12 h ) reduced blood pressure ( 72.5 +/- 1.0 mm Hg c. f. 101.0 +/- 3.6 mm Hg, P < 0.05 ), and
increased plasma NOx ( 153.0 +/- 11.5 muM c. f. 36.2 +/- 3.2 microM, P < 0.05 ), IL-1beta ( 534.0 +/- 93.1 pg/mL c. f. ; 9.6 +/- 9.6 pg/mL, P < 0.05 ),
TNF-alpha ( 88.0 +/- 13.6 pg/mL, P < 0.05 ), inflammatory damage in lung and liver, and mortality
Zhang et al., Exp Toxicol Pathol 2011
(Disease Models, Animal...) :
Moreover, AS inhibited
CLP induced the activation of mitogen activated protein kinases ( MAPKs ) and nuclear factor-?B ( NF-?B ), the expression of cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) protein in lung tissues, and the production of serum
tumor necrosis factor ( TNF-a ) and interleukin-6 (IL-6)
Li et al., Mediators Inflamm 2013
(Lung Injury...) :
In addition, PD inhibited
CLP induced serum
tumor necrosis factor-a (TNF-a) and interleukin-6 (IL-6) production, lung cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase isoform ( iNOS ) protein expressions and NF-?B activation
Jiang et al., J Ethnopharmacol 2013
(Sepsis) :
XBJ significantly reduced the mortality rate, anal temperature and expression of
TNF-a , IL-1ß and IL-6
induced by
CLP