Gene interactions and pathways from curated databases and text-mining

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SPP1 — TGFB1

Text-mined interactions from Literome

Himeno et al., J Bone Miner Res 2002 (Ossification, Heterotopic) : In primary culture of Cbfa1-/- chondrocytes, transforming growth factor (TGF) beta1 , platelet derived growth factor ( PDGF ), interleukin (IL)-1beta, and thyroid hormone ( T3 ) induced osteopontin and MMP-13 expression ... In primary culture of Cbfa1-/- chondrocytes, transforming growth factor (TGF) beta1 , platelet derived growth factor ( PDGF ), interleukin (IL)-1beta, and thyroid hormone ( T3 ) induced osteopontin and MMP-13 expression
Khanna et al., Nephron. Experimental nephrology 2005 : We also examined if CsA- and TAC induced OPN expression is dependent on transforming growth factor ( TGF ) -beta expression
Serlin et al., J Cell Biochem 2006 : Our results demonstrate a potent and dramatic increase in osteopontin expression induced by interleukin-1beta (IL-1beta), whereas tumor necrosis factor-alpha, transforming growth factor-beta , and angiotensin II had minimal effect
Hsieh et al., Kidney Int 2006 (Diabetes Mellitus, Experimental...) : High glucose, angiotensin II, phorbol 12-myristate 13-acetate and transforming growth factor-beta 1 ( TGF-beta1 ) stimulated OPN mRNA expression in IRPTCs in a dose- and time dependent manner
Chen et al., Life Sci 2006 (Anoxia...) : Combined with our previous finding that ANP signaling attenuates transforming growth factor ( TGF ) -beta induced expression of OPN and PN in isolated PASMCs, the current study supports the hypothesis that endogenous ANP plays an important anti-fibrogenic role in the pulmonary vascular adaptation to chronic hypoxia
Li et al., J Appl Physiol 2007 : ANP and cGMP inhibited TGF-beta1 induced pSmad2 and pSmad3 nuclear translocation and expression of periostin, osteopontin , and plasminogen activator inhibitor-1 mRNA and protein, but not TGF-beta1 induced phosphorylation of Smad2 and Smad3
Partridge et al., Matrix Biol 2008 : Subsequent molecular analyses established redox sensitivity of a 200 bp region within the 5 ' UTR of opn promoter and implicated nuclear factor kappa-B and transforming growth factor beta inducible early gene 1 cis acting elements in the regulation of osteopontin
Biros et al., Int J Immunogenet 2009 (Aortic Aneurysm, Abdominal) : This study suggests that polymorphism in TGFBR2 are associated with altered secretion of OPN, supporting a role for transforming growth factor beta in OPN production
Georges et al., Int J Oncol 2010 (Adenocarcinoma...) : Whereas TGF-beta1 induced over-expression of OPN and Runx2 in hepatocytes, it did not exert the same effect on hepatocytes co-cultured with CC531 cells, indicating that this response was abrogated by CC531 cells
Harris et al., J Bone Miner Res 1994 : Effects of transforming growth factor beta on bone nodule formation and expression of bone morphogenetic protein 2, osteocalcin, osteopontin , alkaline phosphatase, and type I collagen mRNA in long-term cultures of fetal rat calvarial osteoblasts
Staal et al., Endocrinology 1996 : Antagonistic effects of transforming growth factor-beta on vitamin D3 enhancement of osteocalcin and osteopontin transcription : reduced interactions of vitamin D receptor/retinoid X receptor complexes with vitamin E response elements
Malyankar et al., Kidney Int 1997 : mRNA stability and nuclear run on assays suggest that induction of osteopontin expression by TGF beta 1 and EGF is via increased transcription of the osteopontin gene