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KLRC1 — TGFB1
Text-mined interactions from Literome
Lee et al., J Immunol 2004
(Colorectal Neoplasms...) :
Modulation of NKG2D by TGF-beta1 was specific, as expression of other NK receptors,
CD94/NKG2A , CD44, CD16, 2B4, or CD56, was not
affected by
TGF-beta1
Friese et al., Cancer Res 2004
(Glioblastoma...) :
Interference with the synthesis of
TGF-beta1 and TGF-beta2 by small interfering RNA technology
prevents the down-regulation of
NKG2D on immune cells mediated by LNT-229 glioma cell supernatant and strongly enhances MICA expression in the glioma cells and promotes their recognition and lysis by CD8 ( + ) T and NK cells
Suvas et al., J Immunol 2006
:
The expression of the inhibitory
CD94-NKG2a molecule could be
induced by
TGF-beta1 , which was shown to present as a bioactive molecule in the latent TG
Bhagat et al., J Clin Invest 2008
(Celiac Disease) :
TCR triggering as well as cross linking of
NKG2A increased both
TGF-beta1 intracellular expression and secretion in vitro
Lee et al., Tumori 2011
(MAP Kinase Signaling System...) :
TGF-BETA1 down-regulated total and surface
NKG2D , which was partially dependent on transcriptional regulation