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COL4A5 — TGFB1

Text-mined interactions from Literome

Grande et al., Experimental biology and medicine (Maywood, N.J.) 2002 : This study examines the role of autocrine versus exogenously added TGF-beta1 in cellular proliferation and collagen IV production, critical targets of TGF-beta1 signaling, using renal cells derived from TGF-beta1 knockout ( KO ) animals or wild-type ( WT ) controls ... These studies provide evidence that autocrine production of TGF-beta1 may play a critical role in regulation of growth and basal collagen IV production by renal tubular epithelial cells
Iglesias-de la Cruz et al., Kidney Int 2002 (Diabetic Nephropathies) : Effects of high glucose and TGF-beta1 on the expression of collagen IV and vascular endothelial growth factor in mouse podocytes ... Effects of high glucose and TGF-beta1 on the expression of collagen IV and vascular endothelial growth factor in mouse podocytes
Yuan et al., Space Med Med Eng (Beijing) 2003 : The expressions of TGF-beta 1 , c-fos and collagen-I declined, but the expression of collagen-IV in pulp vessel increased
Chen et al., J Clin Endocrinol Metab 2005 : Both TGF beta 1 and hypoxia increased fibronectin, collagen I, and collagen IV protein and mRNA in placental fibroblasts
Qi et al., American journal of physiology. Renal physiology 2005 (Fibrosis...) : TGF-beta(1) induced a greater increase in fibronectin and collagen IV secretion in both PTC ( P < 0.01 ) and CF ( P < 0.01 ) compared with that observed with CTGF alone
Qi et al., American journal of physiology. Renal physiology 2006 : Our studies further demonstrate that in the CTGF gene silenced cells, CTGF partially mediates TGF-beta(1) induced fibronectin and collagen IV secretion
Jiang et al., Zhonghua Yi Xue Za Zhi 2005 : [ Effects of aldose reductase on the transforming growth factor-beta1 induced expression of fibronectin and collagen IV : experiment with cultured rat mesangial cells ] ... To study the effects of aldose reductase ( AR ) on the transforming growth factor (TGF)-beta1 induced expression of fibronectin ( FN ) and collagen IV
Sohn et al., Am J Physiol Heart Circ Physiol 2006 : To explore the mechanisms by which LDL regulates CTGF and collagen IV expression in HAECs, we determined first if CTGF and collagen IV are downstream targets for regulation by transforming growth factor-beta ( TGF-beta )
Deng et al., Mol Cell Biochem 2010 : Functionally, TGF-beta1 induced an increase in MMP-9 expression, as well as decreased expression of TIMP-1 and collagen IV , which were all restored by the FAK siRNA transfection
Li et al., Am J Pathol 2010 (Fibrosis) : Resveratrol, an activator of the Nicotinamide adenine dinucleotide ( NAD ) dependent protein deacetylase SIRT1, reversed acetylation but not phosphorylation of Smad3 and inhibited TGF-beta1 induced up-regulation of collagen IV and fibronectin mRNA levels
Jiang et al., Int J Mol Med 2010 (MAP Kinase Signaling System) : Role of cross-talk between the Smad2 and MAPK pathways in TGF-beta1 induced collagen IV expression in mesangial cells ... However, all three MAPK inhibitors reduced collagen IV synthesis induced by TGF-beta1
Grande et al., Lab Invest 1993 : Transforming growth factor-beta 1 induces collagen IV gene expression in NIH-3T3 cells ... TGF-beta 1 induces collagen IV gene expression in both NIH-3T3 cells and normal rat kidney fibroblasts ( NRK-49F cells )
Silbiger et al., Am J Physiol 1998 : In a luciferase reporter gene construct containing the type IV collagen promoter and 1-chain regulatory sequences, we found that TGF-beta1 ( 2 ng/ml ) stimulated alpha1-collagen IV gene transcription in serum-free media ( 140.5 +/- 6.2 relative luciferase units, expressed as a percent of control untreated cells, P < 0.001 )