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BCL10 — TGFB1

Text-mined interactions from Literome

Francis et al., J Biol Chem 2000 : In FDCP-Mix cells, neither IL-3 nor TGF-beta1 induced any change in Bcl-x ( L ) protein levels or the proapoptotic proteins Bad or Bax
Chatzaki et al., Mol Hum Reprod 2003 : We have found the following : ( i ) TGFbeta1 induced apoptosis of stromal cells in a time- and dose dependent manner ; ( ii ) blockade of TGFbeta1 's autocrine/paracrine effect by TGFbeta1 neutralizing antibodies diminished the basal rate of stromal cell apoptosis ; ( iii ) semi-quantitative Western blot analysis showed that TGFbeta1 caused a rapid but transient elevation of the pro-apoptotic FasL protein, without affecting the levels of Fas receptor ; ( iv ) TGFbeta1 increased the levels of the anti-apoptotic Bcl-2 and Bcl-xL proteins, while having no significant effects on the pro-apoptotic proteins Bax and Bak, suggesting the activation of a transient survival mechanism activated in stromal cells as a parallel rescue response to the apoptosis inducing FasL protein
Li et al., Neurotox Res 2010 (Anoxia) : Astrocytes beta ( 8 ) could induce TGF-beta1 leading to upregulation of Bcl-2 and Bcl-xL , and thus attenuated neuronal apoptosis