Passier et al., J Clin Invest 2000
(Cardiomegaly) :
CaM kinase signaling induces cardiac hypertrophy and activates the MEF2 transcription factor in vivo
Boudsocq et al., Nature 2010
(Calcium Signaling...) :
In contrast to negative roles of calmodulin and a calmodulin activated transcription factor in plant defence, the present study reveals Ca ( 2+ ) signalling complexity and demonstrates key positive roles of specific CDPKs in initial MAMP signalling
O'Neill et al., Theriogenology 2012
:
These mediators act via 1-o-phosphatidylinositol-3-kinase signaling which has the dual effects of activating calcium/calmodulin dependent kinase/CREB transcription factor and AKT ( protein kinase B ) /MDM2 mediated survival pathways