Gene interactions and pathways from curated databases and text-mining

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NPPA — SMAD3

Text-mined interactions from Literome

Li et al., J Appl Physiol 2007 : ANP signaling inhibits TGF-beta induced Smad2 and Smad3 nuclear translocation and extracellular matrix expression in rat pulmonary arterial smooth muscle cells ... ANP and cGMP inhibited TGF-beta1 induced pSmad2 and pSmad3 nuclear translocation and expression of periostin, osteopontin, and plasminogen activator inhibitor-1 mRNA and protein, but not TGF-beta1 induced phosphorylation of Smad2 and Smad3
Lo et al., J Cell Biochem 2008 : The present study was performed to explore the effect of ANP on high glucose activated transforming growth factor-beta1 ( TGF-beta1 ), Smad and collagen synthesis in renal proximal epithelial cells