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POMC — PYY

Pathways - manually collected, often from reviews:

• Reactome Reaction: POMC → PYY (reaction) Lerea et al., Neuron 1989, Van Dop et al., Nucleic Acids Res 1989, Itoh et al., J Biol Chem 1988, Takami et al., Brain Res Mol Brain Res 1994

Text-mined interactions from Literome

Acuna-Goycolea et al., J Neurosci 2005 : Peptide YY ( 3-36 ) inhibits both anorexigenic proopiomelanocortin and orexigenic neuropeptide Y neurons : implications for hypothalamic regulation of energy homeostasis
Boey et al., Diabetologia 2006 (Body Weight...) : Pyy knock-out decreased or had no effect on neuropeptide Y expression in the arcuate nucleus of the hypothalamus, and significantly increased proopiomelanocortin expression in this region