Gene interactions and pathways from curated databases and text-mining

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APOA4 — PYY

Text-mined interactions from Literome

Sonoyama et al., Proc Soc Exp Biol Med 2000 : Peptide YY stimulates the expression of apolipoprotein A-IV gene in Caco-2 intestinal cells ... The effect of peptide YY , a gastrointestinal hormone, on the expression of the apolipoprotein A-IV gene in the intestinal epithelial cell line Caco-2 was examined by semiquantitative RT-PCR followed by Southern hybridization with an inner oligonucleotide probe ... Apolipoprotein A-IV mRNA levels were increased in response to peptide YY in a dose- and time dependent fashion
Kalogeris et al., Am J Physiol 1998 : We tested whether exogenous peptide YY (PYY) can stimulate synthesis and lymphatic secretion of intestinal apolipoprotein AIV (apo AIV) ... PYY ( 75-200 pmol. kg-1. h-1 ) stimulated lymphatic apo AIV output from 1.5- to 3.5-fold higher than basal output ... In separate experiments, PYY ( 100 pmol. kg-1. h-1 ) produced a 60 % increase in jejunal mucosal apo AIV synthesis but had no effect on mucosal apo AIV mRNA levels at doses up to 200 pmol