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AKT3 — PTHLH

Text-mined interactions from Literome

Grzesiak et al., Int J Cancer 2005 (Adenocarcinoma...) : These results implicate GSK3 and PKB/Akt in the integrin mediated regulation of PTHrP , IL-6 and IL-8 in pancreatic cancer
Shen et al., Exp Cell Res 2006 (Breast Neoplasms) : PTHrP expression also increased the levels of phosphorylated Akt , with a consequent increase in the levels of phosphorylated ( inactive ) glycogen synthase kinase-3 ( GSK-3 )
Shen et al., Regul Pept 2007 (Colonic Neoplasms...) : PTHrP overexpression also led to an increase in active Akt and inactive GSK-3 levels, indicating that the PTHrP mediated upregulation of integrin alpha6beta4 expression may activate the PI3-K pathway, resulting in increased cell survival, migration and invasion
Agouni et al., Carcinogenesis 2007 (Carcinoma, Renal Cell...) : Interestingly, PTHrP induced phosphorylation of Akt at S473 but had no influence on phosphorylation at T308
Shen et al., Cancer Lett 2007 (Colonic Neoplasms...) : PTHrP increases xenograft growth and promotes integrin alpha6beta4 expression and Akt activation in colon cancer ... Here we observed a positive effect of endogenous PTHrP on LoVo ( human colon cancer ) cell proliferation, migration, invasion, integrin alpha6 and beta4 expression, and p-Akt levels