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FGFR4 — PLCG1

Pathways - manually collected, often from reviews:

• Reactome Reaction: FGFR4 → PLCG1 (indirect_complex) Carpenter et al., Exp Cell Res 1999, Cross et al., J Cell Sci 2000, Hart et al., Oncogene 2000, Chen et al., Oncogene 2005, Hatch et al., J Biol Chem 2006, Cha et al., Mol Cancer Res 2008, Gartside et al., Mol Cancer Res 2009, di Martino et al., Oncogene 2009
• Reactome Reaction: FGFR4 → PLCG1 (reaction) Carpenter et al., Exp Cell Res 1999, Cross et al., J Cell Sci 2000, Hart et al., Oncogene 2000, Chen et al., Oncogene 2005, Hatch et al., J Biol Chem 2006, Cha et al., Mol Cancer Res 2008, Gartside et al., Mol Cancer Res 2009, di Martino et al., Oncogene 2009

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Hprd Interaction: FGFR4 — PLCG1 (in vitro) Vainikka et al., J Biol Chem 1994*

Text-mined interactions from Literome

Shaoul et al., Oncogene 1995 : Both FGFR1 and KGFR induce strong phosphorylation of phospholipase C-gamma and a 90 kDa protein, while FGFR4 induces a relatively weak phosphorylation of phospholipase C-gamma and completely fails to induce phosphorylation of the 90 kDa
Muslin et al., Mol Cell Biol 1994 : Direct activation of phospholipase C-gamma by fibroblast growth factor receptor is not required for mesoderm induction in Xenopus animal caps