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CD3E — PLCG1
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Scholler et al., Eur J Immunol 2000
:
The kinetics of protein complex enhancement correlated with
TCR / CD3 induced tyrosine phosphorylation of
PLCgamma1 ; however, those PLCgamma1 molecules in complex with hSos2 were non phosphorylated after TCR / CD3 stimulation, in contrast to the phosphorylated PLCgamma1 associated with the linker for activation of T cells, LAT
Turka et al., Eur J Immunol 1992
:
Since
TcR/CD3 stimulation of mature T cells
induces tyrosine phosphorylation of
PLC gamma 1 , we investigated this phenomenon in thymocytes, and asked whether ligation of CD45 might regulate this process ... By immunoprecipitation we found that
TcR/CD3 stimulation
induced tyrosine phosphorylation of
PLC gamma 1 , an effect which was enhanced by co-cross linking CD4 to TcR/CD3