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PLA2G1B — SCT
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Chang et al., J Biol Chem 1999
:
Purified porcine pancreatic
PLA2 also
stimulated secretin release concentration-dependently from both STC-1 cells and a mucosal cell preparation enriched in secretin containing endocrine cells isolated from rat duodenum ... The stimulatory
effect of purified pancreatic
PLA2 on
secretin secretion from STC-1 cells was inhibited by an L-type Ca2+ channel blocker, by down-regulation of protein kinase C or by pretreatment of the cell with pertussis toxin
Chang et al., Pancreas 1999
:
Commercially available porcine pancreatic
PLA2 dose-dependently
stimulated secretin release from STC-1 cells ... Porcine pancreatic
PLA2 also
stimulated secretin release from a secretin producing cells enriched preparation isolated from rat duodenal mucosa
Li et al., Am J Physiol Gastrointest Liver Physiol 2001
:
Group I pancreatic
phospholipase A2 (PLA2) in canine pancreatic juice and porcine pancreatic PLA2
stimulate the release of
secretin from both STC-1 cells and a secretin producing cell (S cell) enriched preparation isolated from rat duodenal mucosa ... We investigated the distribution and release of pancreatic
PLA2-like immunoreactivity in the gastrointestinal tract and the
role of PLA2 on the release of
secretin and pancreatic exocrine secretion in response to duodenal acidification in anesthetized rats