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NFAT5 — PIK3R1

Text-mined interactions from Literome

Irarrazabal et al., Proc Natl Acad Sci U S A 2006 : Inhibiting PI3K-IA either by expressing a dominant negative of its regulatory subunit, p85, or by small interfering RNA mediated knockdown of its catalytic subunit, p110alpha, reduces high NaCl induced increases in TonEBP/OREBP transcriptional activity and transactivation, but not nuclear translocation of TonEBP/OREBP, or increases in its abundance ... High NaCl induced increase in TonEBP/OREBP activity is reduced equally by inhibition of ATM or PI3K-IA , and the effects are not additive
Villanueva et al., PloS one 2012 (Reperfusion Injury) : 8 ) Wortmannin, which inhibits ATM and PI3K , reduces hypoxia induced NFAT5 transcriptional activation in HEK293 cells