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OSM — PI3
Text-mined interactions from Literome
Thabard et al., Cytokine 2001
(MAP Kinase Signaling System...) :
In OPM-2 cells, IL-6,
OSM and LIF
induce both signal transducers and activators of transcription ( STAT ), mitogen activated protein kinase ( MAPK ) and
phosphatidylinositol 3-kinase (PI 3-K) activation
Luyckx et al., American journal of physiology. Renal physiology 2009
(Acute-Phase Reaction) :
OSM induced a significant increase in expression of FGB, OSMR, serpin
peptidase inhibitor A1, IL-6, and lipopolysaccharide binding protein, and a decrease in IL-6R