UCSC Genome Browser Gene Interaction Graph

JavaScript is disabled in your web browser

You must have JavaScript enabled in your web browser to use the Genome Browser

Gene interactions and pathways from curated databases and text-mining

◀ Back to NR1H3

NR1H3 — RXRG

Pathways - manually collected, often from reviews:

KEGG PPAR signaling pathway: Complex of PPARA-RXRA-RXRB-RXRG → NR1H3 (gene expression, expression)
KEGG PPAR signaling pathway: Complex of PPARG-RXRA-RXRB-RXRG → NR1H3 (gene expression, expression)
NCI Pathway Database RXR and RAR heterodimerization with other nuclear receptor: RXRs/LXRs/DNA/9cRA complex (NR1H3_NR1H2-RXRB_RXRG_RXRB_RXRA) → Oxysterols (/) (modification, collaborate) Willy et al., Genes Dev 1995, Miyata et al., J Biol Chem 1996
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database RXR and RAR heterodimerization with other nuclear receptor: RXRs/LXRs/DNA/9cRA complex (NR1H3_NR1H2-RXRB_RXRG_RXRB_RXRA) → None (modification, collaborate) Willy et al., Genes Dev 1995, Miyata et al., J Biol Chem 1996
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database RXR and RAR heterodimerization with other nuclear receptor: RXRs/LXRs/DNA/9cRA complex (NR1H3_NR1H2-RXRB_RXRG_RXRB_RXRA) → RXRs/LXRs/DNA complex (RXRB_RXRG_RXRB_RXRA-NR1H3_NR1H2) (modification, collaborate)
Willy et al., Genes Dev 1995, Miyata et al., J Biol Chem 1996
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database RXR and RAR heterodimerization with other nuclear receptor: RXRs/LXRs/DNA/9cRA complex (NR1H3_NR1H2-RXRB_RXRG_RXRB_RXRA) → RXRs/LXRs/DNA/Oxysterols complex (RXRB_RXRG_RXRB_RXRA-NR1H3_NR1H2-_compound:CAS566-26-7_compound:CAS474-73-7_) (modification, collaborate)
Willy et al., Genes Dev 1995, Miyata et al., J Biol Chem 1996
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database RXR and RAR heterodimerization with other nuclear receptor: RXRs/LXRs/DNA/9cRA complex (NR1H3_NR1H2-RXRB_RXRG_RXRB_RXRA) → RXRs/LXRs/DNA/Oxysterols complex (RXRB_RXRG_RXRB_RXRA-NR1H3_NR1H2-_compound:CAS566-26-7_compound:CAS474-73-7_) (modification, collaborate)
Willy et al., Genes Dev 1995, Miyata et al., J Biol Chem 1996
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database RXR and RAR heterodimerization with other nuclear receptor: Oxysterols (/) → RXRs/LXRs/DNA complex (RXRB_RXRG_RXRB_RXRA-NR1H3_NR1H2) (modification, collaborate)
Willy et al., Genes Dev 1995, Miyata et al., J Biol Chem 1996
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database RXR and RAR heterodimerization with other nuclear receptor: Oxysterols (/) → RXRs/LXRs/DNA/Oxysterols complex (RXRB_RXRG_RXRB_RXRA-NR1H3_NR1H2-_compound:CAS566-26-7_compound:CAS474-73-7_) (modification, collaborate)
Willy et al., Genes Dev 1995, Miyata et al., J Biol Chem 1996
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database RXR and RAR heterodimerization with other nuclear receptor: Oxysterols (/) → RXRs/LXRs/DNA/Oxysterols complex (RXRB_RXRG_RXRB_RXRA-NR1H3_NR1H2-_compound:CAS566-26-7_compound:CAS474-73-7_) (modification, collaborate)
Willy et al., Genes Dev 1995, Miyata et al., J Biol Chem 1996
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database RXR and RAR heterodimerization with other nuclear receptor: None → RXRs/LXRs/DNA complex (RXRB_RXRG_RXRB_RXRA-NR1H3_NR1H2) (modification, collaborate)
Willy et al., Genes Dev 1995, Miyata et al., J Biol Chem 1996
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database RXR and RAR heterodimerization with other nuclear receptor: None → RXRs/LXRs/DNA/Oxysterols complex (RXRB_RXRG_RXRB_RXRA-NR1H3_NR1H2-_compound:CAS566-26-7_compound:CAS474-73-7_) (modification, collaborate)
Willy et al., Genes Dev 1995, Miyata et al., J Biol Chem 1996
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database RXR and RAR heterodimerization with other nuclear receptor: None → RXRs/LXRs/DNA/Oxysterols complex (RXRB_RXRG_RXRB_RXRA-NR1H3_NR1H2-_compound:CAS566-26-7_compound:CAS474-73-7_) (modification, collaborate)
Willy et al., Genes Dev 1995, Miyata et al., J Biol Chem 1996
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database RXR and RAR heterodimerization with other nuclear receptor: RXRs/LXRs/DNA complex (RXRB_RXRG_RXRB_RXRA-NR1H3_NR1H2) → RXRs/LXRs/DNA/Oxysterols complex (RXRB_RXRG_RXRB_RXRA-NR1H3_NR1H2-_compound:CAS566-26-7_compound:CAS474-73-7_) (modification, collaborate)
Willy et al., Genes Dev 1995, Miyata et al., J Biol Chem 1996
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database RXR and RAR heterodimerization with other nuclear receptor: RXRs/LXRs/DNA complex (RXRB_RXRG_RXRB_RXRA-NR1H3_NR1H2) → RXRs/LXRs/DNA/Oxysterols complex (RXRB_RXRG_RXRB_RXRA-NR1H3_NR1H2-_compound:CAS566-26-7_compound:CAS474-73-7_) (modification, collaborate)
Willy et al., Genes Dev 1995, Miyata et al., J Biol Chem 1996
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database RXR and RAR heterodimerization with other nuclear receptor: RXRs/LXRs/DNA/Oxysterols complex (RXRB_RXRG_RXRB_RXRA-NR1H3_NR1H2-_compound:CAS566-26-7_compound:CAS474-73-7_) → RXRs/LXRs/DNA/Oxysterols complex (RXRB_RXRG_RXRB_RXRA-NR1H3_NR1H2-_compound:CAS566-26-7_compound:CAS474-73-7_) (modification, collaborate)
Willy et al., Genes Dev 1995, Miyata et al., J Biol Chem 1996
Evidence: mutant phenotype, assay, physical interaction
WikiPathways PPAR signaling pathway: Complex of RXRA-PPARA-RXRG-RXRB → CYP8B1/NR1H3/CYP27A1/CYP7A1 (mim-transcription-translation)
WikiPathways PPAR signaling pathway: Complex of PPARG-RXRA-RXRG-RXRB → CYP8B1/NR1H3/CYP27A1/CYP7A1 (mim-transcription-translation)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

IRef Bind_translation Interaction: RXRG — NR1H3 (two hybrid) Albers et al., Mol Cell Proteomics 2005
IRef Biogrid Interaction: RXRG — NR1H3 (direct interaction, two hybrid) Albers et al., Mol Cell Proteomics 2005
IRef Hprd Interaction: NR1H3 — RXRG (two hybrid) Albers et al., Mol Cell Proteomics 2005
IRef Intact Interaction: RXRG — NR1H3 (physical association, two hybrid) Yu et al., Nat Methods 2011