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MMP2 — NOS1

Text-mined interactions from Literome

Novaro et al., Reprod Fertil Dev 2001 : In addition, we demonstrated a positive regulatory role of NO on the activity and protein expression of MMP-2 and MMP-9, because NO donors ( NOC-18 and spermine-NONOate ) or the NOS substrate ( L-arginine ) stimulate, whereas NOS inhibitors ( N ( G ) -nitro-L-arginine methyl ester and N ( G ) -monomethyl-L-arginine ) reduce the expression and gelatinolytic activity of MMP-2 and MMP-9 in isolated trophoblast cells
Johanning et al., Ann Vasc Surg 2002 (Aortic Aneurysm, Abdominal) : Nitric oxide synthase (NOS) expression, hemodynamic consequences of NO inhibition, and the effect of NO on matrix metalloproteinase ( MMP ) expression during aneurysm formation are unknown
Eagleton et al., J Surg Res 2002 : This study tested the hypothesis that nitric oxide synthase (NOS) inhibition in whole aortic wall causes increases in cytokine stimulated MMP and TIMP expression
Choe et al., J Cosmet Sci 2003 : In this work, we initially examined the effect of nitric oxide ( NO ) and nitric oxide synthase (NOS) inhibitors on the production of MMP-1 and MMP-2 by human dermal fibroblasts ( HDF )
Robinson et al., Shock 2006 (Endotoxemia) : Therefore, the purpose of these studies was to compare the effects of selective and nonselective NOS inhibition on LPS induced gastric MMP production ... The ability of selective iNOS inhibition to ameliorate LPS induced gastric injury may be due in part to its inhibition of active MMP-2 production, whereas nonselective NOS inhibitors increase MMP-2 levels and maintain gastric injury after LPS administration
Yang et al., Neurol Res 2007 (Brain Ischemia...) : In the presence of a nitric oxide synthase (NOS) inhibitor, N ( omega ) -nitro-L-arginine methyl ester ( L-NAME ), the expression levels of MMP-2 were decreased, but the expression of MMP-9 was not decreased by agmatine administration
Pustovrh et al., Reproduction 2007 (Diabetes Mellitus, Experimental) : In addition, while a NO donor enhanced MMP2 and MMP9 activities, a NOS inhibitor reduced these activities in the maternal side of the placenta from control rats
Lukivskaya et al., Eur J Clin Invest 2008 (Disease Models, Animal...) : Both NOS inhibitors up-regulated procollagen alpha1 ( I ), MMP-13 , TIMP-1 and PAI-1 mRNA expression
Chen et al., Tokai J Exp Clin Med 2008 (Plaque, Atherosclerotic) : Activation of inducible nitric oxide synthase increases MMP-2 and MMP-9 levels in ApoE-knockout mice
da Costa et al., Naunyn Schmiedebergs Arch Pharmacol 2012 (Disease Models, Animal...) : These findings indicate that ASE produces antihypertensive effect and prevents the endothelial dysfunction and vascular structural changes in 2K-1C hypertension, probably through mechanisms involving antioxidant effects, NOS activation, and inhibition of MMP-2 activation
Souza-Pinto et al., J Biomed Mater Res A 2013 (Inflammation) : Inducible nitric oxide synthase inhibition increases MMP-2 activity leading to imbalance between extracellular matrix deposition and degradation after polypropylene mesh implant