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NGF — THY1

Text-mined interactions from Literome

Dickson et al., EMBO J 1986 : The effect of nerve growth factor (NGF) on the expression of neurofilament and Thy-1 genes in rat PC12 pheochromocytoma cells was examined at both the transcriptional and post-transcriptional levels
Mann et al., J Neurochem 1989 : In contrast, over the same period of culture, cholera toxin inhibited the NGF induction of Thy-1 and L1
Doherty et al., J Neurochem 1987 (Adrenal Gland Neoplasms...) : With primed PC12 cells, NGF induced a rapid increase in Thy-1 expression over a time course similar to that of neurite regeneration, with half-maximal and maximal increases apparent at 0.6 and 6 ng/ml NGF ... Cholera toxin and dibutyryl cyclic AMP, but not B-cholera toxin or antibodies to the toxin receptor, were found to inhibit NGF induced increases in Thy-1 ... Despite showing a synergistic effect on morphological differentiation, cholera toxin was again found to inhibit NGF induced increases in Thy-1 expression in cultures of naive PC12 cells
Doherty et al., J Cell Biol 1988 (Pheochromocytoma) : Comparison of the effects of NGF , activators of protein kinase C, and a calcium ionophore on the expression of Thy-1 and N-CAM in PC12 cell cultures ... Phorbol ester derivatives capable of activating Ca2+/phospholipid dependent protein kinase ( protein kinase C ) and the calcium ionophore A23187 were found to mimic the NGF induction of Thy-1 , but not N-CAM ... Treatment of PC12 cells with high concentrations of phorbol esters was found to inhibit the NGF induction of Thy-1 , but not N-CAM ... Whereas the above results are consistent with activation of protein kinase C underlying the NGF induction of Thy-1 , the same data are not consistent with this pathway being important in the N-CAM response
Doherty et al., Development 1987 (Glioma) : The growth of PC12 cells on a collagen substratum or on monolayers of several non-neuronal cell types was studied by measuring nerve growth factor (NGF) dependent increases in the expression of a 150 X 10 ( 3 ) ( Mr ) neurofilament protein subunit and the membrane glycoprotein Thy-1