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NFKB1 — QRICH2
Text-mined interactions from Literome
James et al., Diabetes 2002
(Hyperinsulinism) :
Overexpression of
glutamine : fructose-6-phosphate amidotransferase ( GFAT ), the rate limiting enzyme for flux through the hexosamine pathway,
led to a 2.2-fold increase in
NF-kappaB enhancer activity ; the combination of GFAT overexpression and high glucose increased activity 2.8-fold, and these increases were prevented by 40 micromol/l O-diazoacetyl-L-serine ( azaserine ) or 6-diazo-5-oxonorleucine
Fillmann et al., Toxicology 2007
(Colitis...) :
We investigated the
effects of
glutamine on markers of oxidative stress,
nuclear factor kappaB (NF-kappaB) activation, and pro-inflammatory mediators in a rat model of experimental colitis induced by intracolonic administration of 7 % acetic acid
Kretzmann et al., Inflamm Bowel Dis 2008
(Colitis...) :
We investigated the
effects of
glutamine on proinflammatory gene expression and activation of
nuclear factor kappa B (NF-kappaB) and signal transducers and activators of transcription ( STAT ) in a rat model of experimental colitis
Zhang et al., Inflammation 2008
(Inflammation) :
As a precursor of GSH,
glutamine could
prevent the
NF-kappaB activation and attenuate the release of TNF-alpha in LPS stimulated AT-II cells and the effect may be mediated via GSH synthesis