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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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ADAM17 — NFKB1

Text-mined interactions from Literome

Pradillo et al., J Cereb Blood Flow Metab 2005 (Brain Ischemia) : In summary, these data show that IPC produces neuronal upregulation of TACE and TNFR1, and that the pathway TACE/TNF-alpha/TNFR1/NF-kappaB is involved in IT
Scherübl et al., Journal of inflammation (London, England) 2005 : Surface expressed hicp75TNFR behaves like hp75TNFR demonstrating susceptibility for TACE induced shedding and NFkappaB activation after TNF binding
Csiszar et al., J Appl Physiol 2008 (Cardiovascular Diseases...) : In the present review we summarize recent experimental data suggesting that mitochondrial production of reactive oxygen species, innate immunity, the local TNF-alpha converting enzyme (TACE)-TNF-alpha , and the renin-angiotensin system may underlie NF-kappaB induction and endothelial activation in aged arteries