Gene interactions and pathways from curated databases and text-mining

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HLA-DRB1 — MCL1

Text-mined interactions from Literome

Shankar et al., Mol Cancer Ther 2008 (Neoplasm Metastasis...) : DATS induced the expression of DR4, DR5 , Bax, Bak, Bim, Noxa, and PUMA and inhibited expression of Mcl-1 , Bcl-2, Bcl-X ( L ), survivin, XIAP, cIAP1, and cIAP2
Qin et al., Biochem Biophys Res Commun 2010 (Melanoma...) : AOA did not influence TRAIL DR4 or DR5 cell surface death receptor levels, but AOA enhanced pro-apoptotic protein levels of Noxa, while reducing pro-survival protein Mcl-1