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MAPK1 — MUC5AC

Text-mined interactions from Literome

Takeyama et al., J Immunol 2000 (MAP Kinase Signaling System) : Neutrophil supernatant induced EGFR tyrosine phosphorylation, activation of p44/42mapk , and MUC5AC synthesis were inhibited by antioxidants ( N-acetyl-cysteine, DMSO, dimethyl thiourea, or superoxide dismutase ) ; neutralizing Abs to EGFR ligands ( EGF and TGF-alpha ) were without effect, and no TGF-alpha protein was found in the neutrophil supernatant ... In contrast, the EGFR ligand, TGF-alpha, increased EGFR tyrosine phosphorylation, activation of p44/42mapk , and subsequent MUC5AC synthesis, but these effects were not inhibited by antioxidants
Casalino-Matsuda et al., Am J Respir Cell Mol Biol 2009 : We have previously shown that ROS induced MUC5AC expression in NHBE cells is dependent on hyaluronan depolymerization and epidermal growth factor receptor (EGFR)/mitogen activated protein kinase ( MAPK ) activation
Kim et al., J Cell Biochem 2009 : We examined the role of mitogen activated protein kinase ( MAPK ) signaling on MUC5AC gene expression in airway epithelium
Yang et al., Ann Hepatol 2013 (Cholelithiasis) : Expression of phosphorylated p38MAPK was upregulated by exogenous PGE2, and p38MAPK inhibitor reduced MUC2 and MUC5AC expression in HIBECs