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AKT2 — LRP5

Text-mined interactions from Literome

An et al., Blood 2008 (Brain Ischemia...) : We found that, in the early phases of the ischemic insult, the interaction between tPA and LRP induces Akt phosphorylation ( pAkt ) in perivascular astrocytes and inhibits pAkt in neurons
Sunters et al., J Biol Chem 2010 : Mechano-transduction in osteoblastic cells involves strain regulated estrogen receptor alpha mediated control of insulin-like growth factor (IGF) I receptor sensitivity to Ambient IGF, leading to phosphatidylinositol 3-kinase/AKT dependent Wnt/LRP5 receptor independent activation of beta-catenin signaling