Murph et al., J Cell Sci 2003
:
In addition, both dynamin2 K44A and Rab5 S34N mildly inhibited LPA1 dependent activation of serum response factor Murph et al., Biochim Biophys Acta 2008
(Disease Progression...) :
Mutagenesis data supports the notion that Thr-236 regulates this process since mutating Thr-236 to Ala-236 increased basal and LPA mediated serum response factor (SRF) signaling activity and Lys-236 further increased this basal signaling
Price et al., Philos Trans R Soc Lond B Biol Sci 1996
:
In contrast, activation of the SRE by whole serum and the mitogenic phospholipid LPA requires SRF binding alone
Mao et al., J Biol Chem 1998
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And RGS12, but not other RGS proteins, blocked thrombin- and LPA mediated SRF activation in the Galphaq/11-deficient cells