Cui et al., Arterioscler Thromb Vasc Biol 2003
:
Phosphorylation of mitogen activated protein kinase kinase ( MEK ) and extracellular signaling regulated kinases ( ERK1/2 ) was rapidly and markedly induced by LPA Bian et al., Cancer Res 2004
(MAP Kinase Signaling System...) :
In this article, we demonstrate that LPA activates mitogen activated protein kinase kinase 1 ( MEKK1 ) in a G ( i ) -Ras dependent manner and that MEKK1 activity is essential for LPA stimulated ovarian cancer cell migration