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CPOX — LPA

Text-mined interactions from Literome

Shida et al., World J Gastroenterol 2005 (Colonic Neoplasms) : To examine whether lysophosphatidic acid (LPA) induces phosphorylation of c-Met and epidermal growth factor receptor (EGFR), both of which have been proposed as prognostic markers of colorectal cancer, and whether LPA induces cyclooxygenase-2 (COX-2) expression in human colon cancer cells
He et al., Biochem J 2008 : The present study provides evidence that LPA induced transactivation of EGFR regulates COX ( cyclo-oxygenase)-2 expression and PGE ( 2 ) [ PG ( prostaglandin ) E ( 2 ) ] release through the transcriptional factor, C/EBPbeta ( CCAAT/enhancer binding protein beta ), in HBEpCs