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IRF7 — TCF4
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Shinohara et al., Nat Immunol 2006
:
Shortly after TLR9 engagement, colocalization of Opn-i and the adaptor molecule MyD88 was associated with induction of
transcription factor IRF7 dependent IFN-alpha gene expression, whereas deficient expression of Opn-i was associated with defective nuclear translocation of IRF7 in pDCs
Watanabe et al., J Clin Invest 2010
(Helicobacter Infections) :
IRF7 induced IFN-beta production, which led to activation of a heterotrimeric
transcription factor complex known as IFN stimulated gene factor 3 ( ISGF3 ) and the subsequent production of CXCL10 and additional type I IFN
Liang et al., J Immunol 2011
:
Negative
regulation of
IRF7 activation by activating
transcription factor 4 suggests a cross-regulation between the IFN responses and the cellular integrated stress responses