Gene interactions and pathways from curated databases and text-mining

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IRF6 — PRL

Text-mined interactions from Literome

De Laurentiis et al., Neuroimmunomodulation 2002 (Bacterial Infections...) : This increase in dopaminergic activity could mediate the inhibitory effect of LPS and TNF-alpha on prolactin release
De Laurentiis et al., Regul Pept 2003 : Since neurokinin A ( NKA ) plays a role in inflammatory responses and is involved in the control of prolactin secretion, we examined the in vivo effect of LPS on the concentration of NKA in hypothalamus and pituitary ( assessed by RIA ) and serum prolactin levels in male rats
Caruso et al., Neuroendocrinology 2004 : HS024 failed to modify the inhibitory effects of LPS and alpha-MSH on prolactin release but reverted the effect of LPS on LH secretion, indicating that MC4-R activation may be involved in the effects of alpha-MSH on LH secretion in male rats
Carr et al., Life Sci 1987 : The effects of LPS on ovine prolactin ( oPRL ) binding by hepatic membranes of lactating mice is explored in this report
Theas et al., Endocrine 1998 : Our results also indicate that LPS inhibits prolactin release in an estrogenic environment, suggesting that TNF-alpha could affect pituitary hormone release during endotoxemia
Knigge et al., Neuroendocrinology 1999 : LPS had no effect on PRL secretion ... Bilateral lesion of the posterior hypothalamus inhibited the ACTH, beta-END and PRL responses to restraint stress, ether stress and LPS endotoxin, whereas sham operation had no effect compared to nonoperated control rats ... Furthermore, in accordance with our previous findings, the lesion experiments indicated the existence of an interaction between the histaminergic and serotonergic system in regulation of the stress- and LPS induced PRL release