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INS — MCOLN1
Text-mined interactions from Literome
King et al., Am J Physiol 1976
:
Chicken
insulin secretory
responses to glucose, glucagon, tolbutamide, and lack of
Mg2+ were measured using isolated perfused in situ chicken pancreata
Murakami et al., Proc Soc Exp Biol Med 1992
(Insulinoma...) :
An absence of
Mg2+ in the extracellular space may
result in enhanced
insulin secretion
Hwang et al., Biochim Biophys Acta 1991
:
Mg2+ inhibits the specific [ 3H ]
Ins ( 1,4,5 ) P3 binding
Nagy et al., Endocrinology 1990
(Insulin Resistance) :
The effects of insulin receptor antibodies on basal and
insulin stimulated ( Ca2+ +
Mg2+ ) ATPase activities were specific
Levy et al., Diabetes 1986
(Diabetes Mellitus, Experimental...) :
The direct
effect of
insulin on the high-affinity
Ca2+-Mg2+-ATPase was studied in kidney proximal tubular basolateral membranes (BLM) obtained from control and streptozocin induced non-insulin dependent diabetes mellitus ( NIDDM ) rats ...
Insulin ( 16-200 microU/ml ) significantly
increased the high-affinity
Ca2+-Mg2+-ATPase activity ( 17-40 % ) in membranes from control animals but had no effect on the enzyme activity in the membranes from the NIDDM rats
Agarwal et al., Acta Diabetol Lat 1985
(Diabetes Mellitus, Experimental) :
The in vitro
effect of porcine
insulin on Na+ + K+, Ca2+- and
Mg2+-ATPases of the rat erythrocyte membrane of normal and alloxan induced diabetic rats was investigated
Levy et al., Endocrinology 1986
:
At 0.1 microM free Ca2+,
insulin ( 25-100 microU/ml )
increased ( Ca2+ +
Mg2+ ) ATPase activity in a dose dependent manner by 35-52 % ( P less than 0.01 ) and by 8-13 % ( P less than 0.05 to P less than 0.01 ) at a 3-microM free Ca2+ concentration ; hPTH- ( 1-34 ) PTH ( 10 ( -9 ) -10 ( -7 ) M ) increased the enzyme activity at a free Ca2+ concentration of 0.1 microM by 13-25 % ( P less than 0.05 to P less than 0.01 )
Inoue et al., Brain Res 1995
:
The AlF
INS in the
presence of 12 microM
Mg2+ reversed polarity at about +9 mV, irrespective of the extent of decline
Malaisse et al., Diabete Metab 1976
:
Mg2+ in high concentration ( 10 to 20 mEq/l )
caused a dose related inhibition of glucose induced 45calcium net uptake and subsequent
insulin release in isolated islets
Van Delden et al., J Biol Chem 1993
(Leukemia, Promyelocytic, Acute) :
The
effects of Ca2+ and
Mg2+ on
Ins ( 1,4,5 ) P3 binding were conserved after solubilization of HL-60 membranes ...
Mg2+ acts either directly on the
Ins ( 1,4,5 ) P3 receptor or on a closely associated target