Black et al., Pediatr Res 1992
:
Although EGF and insulin modestly increased apo A-IV synthesis, the combination of insulin and hydrocortisone treatment up-regulated apo A-IV synthesis by 2.6-fold
Uchida et al., Atherosclerosis 1991
:
Insulin stimulated the production of albumin, but inhibited the production of apo A-IV dose-dependently
LeBoeuf et al., J Lipid Res 1994
:
This suggests that factors thought to be mediated by insulin , ( e.g., plasma free fatty acid concentrations ; hepatic apoA-IV mRNA levels ) may be influenced by local changes in insulin sensitivity, which are controlled genetically and are not reflected by plasma insulin levels