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IL6ST — OSM

Pathways - manually collected, often from reviews:

• KEGG Cytokine-cytokine receptor interaction: OSM → Complex of IL6ST-LIFR (protein-protein, activation)
• KEGG Cytokine-cytokine receptor interaction: OSM → Complex of IL6ST-OSMR (protein-protein, activation)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Dip Interaction: IL6ST — OSM (physical association, coimmunoprecipitation) Mosley et al., J Biol Chem 1996*
• IRef Hprd Interaction: OSM — IL6ST (in vitro) He et al., FEBS Lett 2005*, Mosley et al., J Biol Chem 1996*
• IRef Intact Interaction: IL6ST — OSM (direct interaction, pull down) He et al., FEBS Lett 2005*
• IRef Ophid Interaction: IL6ST — OSM (aggregation, interologs mapping) Brown et al., Bioinformatics 2005
• IRef Ophid Interaction: IL6ST — OSM (aggregation, confirmational text mining) Mosley et al., J Biol Chem 1996*

Text-mined interactions from Literome

Hurst et al., J Immunol 2002 (Bacterial Infections...) : Stimulation of human peritoneal mesothelial cells with OSM induced phosphorylation of gp130 and OSM receptor beta, which was accompanied by activation of STAT3 and secretion of CC chemokine ligand 2/monocyte chemoattractant protein-1 and IL-6
Auernhammer et al., J Endocrinol 2004 (Adrenal Cortex Neoplasms) : The effects of murine oncostatin M ( mOSM ) are specifically mediated by the heterodimeric oncostatin M receptor (OSMR)/gp130 receptor complex