Gene interactions and pathways from curated databases and text-mining

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IL1A — MRXS5

Text-mined interactions from Literome

Irahara et al., Biol Reprod 1999 : The dexamethasone effect was not limited to the IL-1 mediated induction of PGS-2 transcripts, comparable suppression being noted for the IL-1 mediated up-regulation of ovarian transcripts corresponding to IL-1beta, the IL-1 receptor antagonist, and the type I IL-1 receptor
Rauk et al., Am J Reprod Immunol 2000 : With intrauterine infection, IL-1 may induce labor through the autocrine production of uterotonic PGs
Matzkin et al., Mol Cell Endocrinol 2012 (MAP Kinase Signaling System) : Our studies suggest that PRL induces COX2/PGs in hamster Leydig cells through IL-1ß and activation of P38-MAPK and JAK2
Dingle et al., J Lipid Mediat 1993 (Osteoarthritis) : ( 2 ) The synthesis of IL1 can be controlled by prostaglandins (PGs) , which may explain why the inhibitory action can be at least partially overcome by the action of the PG analogue Misoprostol in the dose range 10-100 ng/ml
Watanobe et al., Cytokine 1995 : Many studies have reported that prostaglandins (PGs) , especially PGE2, in the brain may mediate the IL-1 stimulation of corticotropin releasing hormone release, which then leads to adrenocorticotropin ( ACTH ) secretion
Kol et al., Endocrinology 1997 : These observations support the proposition that PLA2 may be a key component in the IL-1 stimulated biosynthesis of ovarian PGs