Gene interactions and pathways from curated databases and text-mining

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HNF4A — IL1A

Text-mined interactions from Literome

Jahan et al., Am J Physiol Gastrointest Liver Physiol 2005 (MAP Kinase Signaling System) : Furthermore, IL-1beta inhibited HNF4alpha gene transcription, protein expression, and binding to the CYP8B1 gene
Li et al., Hepatology 2006 : In conclusion, IL-1 beta and CDCA inhibit HNF4 alpha but induce c-Jun, which in turn blocks HNF 4 alpha recruitment of PGC-1 alpha to the CYP7A1 chromatin and results in inhibition of CYP7A1 gene transcription