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CEACAM1 — IL1A

Text-mined interactions from Literome

Gonzalez et al., Mol Hum Reprod 2011 : CEACAM1 , an adhesion molecule implicated in trophoblast invasion, was up-regulated in AC-1M88 cells by conditioned medium from decidualized ESC, and by HB-EGF, IL-1ß and LIF in combination
Lu et al., PLoS Pathog 2012 (Inflammation...) : CEACAM1 negatively regulates IL-1ß production in LPS activated neutrophils by recruiting SHP-1 to a SYK-TLR4-CEACAM1 complex ... Since neutrophils have abundant expression of the ITIM containing co-receptor CEACAM1 and Gram negative bacteria such as Neisseria utilize CEACAM1 as a receptor that inhibits inflammation, we hypothesized that the overall production of IL-1ß in LPS treated neutrophils may be negatively regulated by CEACAM1