Gene interactions and pathways from curated databases and text-mining

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IL13 — SOCS3

Text-mined interactions from Literome

Hebenstreit et al., Mol Immunol 2005 : SOCS-1 and SOCS-3 inhibit IL-4 and IL-13 induced activation of Eotaxin-3/CCL26 gene expression in HEK293 cells
Albanesi et al., J Immunol 2007 : We further demonstrate that IL-4 and IL-13 activate STAT-6 and induce the suppressors of cytokine signaling (SOCS)-1 and -3
Kleinsteuber et al., Blood 2012 (Tuberculosis) : SOCS3 promotes interleukin-17 expression of human T cells
Romain et al., Arterioscler Thromb Vasc Biol 2013 (Aortic Aneurysm, Abdominal...) : Overexpression of SOCS3 in T lymphocytes leads to impaired interleukin-17 production and severe aortic aneurysm formation in mice -- brief report
Park et al., J Allergy Clin Immunol 2013 (Nasal Polyps...) : Nasal epithelial cell culture was used to elucidate the effect of IL-4, IL-5, IL-6, IL-10, IL-13 , IFN-?, TNF-a, and TGF-ß1 on SOCS1 and SOCS3 expression in sinus mucosa ... SOCS1 was induced by IL-4, IL-13 , IFN-?, and TNF-a, while SOCS3 expression was upregulated by IL-6, IL-13, IFN-?, and TNF-a