Gene interactions and pathways from curated databases and text-mining

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IFNA8 — JAK3

Text-mined interactions from Literome

Li et al., Oncogene 1999 : The human papilloma virus ( HPV ) -18 E6 oncoprotein physically associates with Tyk2 and impairs Jak-STAT activation by interferon-alpha
Joo et al., Arch Pharm Res 2006 : In our study, we were able to determine that DDB stimulates Jak/Stat signaling, and induces the expression of interferon alpha ( IFN-alpha ) stimulated genes, most notably 6-16 and ISG12
Wang et al., Nat Immunol 2008 : CaMK and Pyk2 relayed signals from integrins and the ITAM containing adaptor DAP12 to augment interleukin 10- and interferon-alpha induced Jak activation and STAT1 dependent gene expression