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Ahmad et al., Am J Physiol Heart Circ Physiol 2009
:
Treatment of
HO-1 induced
BPA with extracellular catalase resulted in reversal of the attenuation of HPV without affecting the force development to KCl. Increasing intracellular peroxide scavenging with 0.1 mM ebselen increased force development to KCl and partially reversed the decrease in HPV seen on induction of HO-1
Chepelev et al., Chem Res Toxicol 2013
:
Furthermore,
BPA increased the transactivation activity of ectopic Nrf1 and Nrf2 and
increased the expression of ARE-target genes
ho-1 and nqo1 at high ( 100-200 µM ) BPA concentrations only