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GPR68 — RHO

Text-mined interactions from Literome

Chatah et al., J Biol Chem 2001 : Thus, these findings suggest that stimulation of a G-protein coupled receptor ( PAR1 ) leads to the sequential activation of G alpha ( q ), Rac, Rho , and PIP5K I alpha
Li et al., Journal of molecular signaling 2013 : Over-expression of OGR1 in MCF7 cells substantially enhanced activation of Rho and inhibition of Rac1, resulting in inhibition of cell migration ... In addition, expression of the Ga12/13 specific regulator of G protein signaling (RGS) domain of p115RhoGEF, but not treatment with pertussis toxin ( PTX, a Gai specific inhibitor ), could abrogate OGR1 dependent Rho activation, Rac1 inactivation, and inhibition of migration in MCF7 cells