◀ Back to FMR1

FMR1 — GRM5

Text-mined interactions from Literome

Yan et al., Neuropharmacology 2005 (Epilepsy, Reflex...) : Examination of phenotypes combining mGluR5 inhibition and Fmr1 mutation indicated that absence of FMRP may affect mGluR5 signaling through indirect as well as direct pathways
Higashimori et al., Hum Mol Genet 2013 (Fragile X Syndrome) : Astroglial FMRP dependent translational down-regulation of mGluR5 underlies glutamate transporter GLT1 dysregulation in the fragile X mouse ... In summary, our results provide evidence that FMRP positively regulates translational expression of mGluR5 in astroglial cells, and FMRP dependent down-regulation of mGluR5 underlies GLT1 dysregulation in fmr1 ( -/- ) astrocytes