Gene interactions and pathways from curated databases and text-mining

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CCNB1 — E2F1

Text-mined interactions from Literome

Lukas et al., Nature 1999 : Accumulation of cyclin B1 requires E2F and cyclin-A dependent rearrangement of the anaphase promoting complex
Park et al., Carcinogenesis 2001 (Prostatic Neoplasms) : Accompanying this is a reduction in the E2F-1 regulated expression of cell cycle genes such as c-myc, cyclin D1, cyclin A and cyclin B1
Russo et al., Cancer Res 2006 (Bone Neoplasms...) : E2F-1 overexpression in U2OS cells increases cyclin B1 levels and cdc2 kinase activity and sensitizes cells to antimitotic agents