Gene interactions and pathways from curated databases and text-mining

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DUSP1 — TRH

Text-mined interactions from Literome

Ryser et al., J Biol Chem 2001 : Ca ( 2+ ) signals are necessary for the induction of MKP-1 in response to TRH but not to EGF
Ryser et al., Biochem J 2004 (MAP Kinase Signaling System) : In the pituitary cell line GH4C1, MKP-1 gene transcription is strongly induced by thyrotropin releasing hormone (TRH) as well as by epidermal growth factor (EGF) as a consequence of activated MAPK/extracellular-signal regulated kinase ( ERK ) signalling