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DUSP1 — LPA

Text-mined interactions from Literome

Li et al., J Cell Biochem 2010 : Interestingly, p38 activation, a common process mediating various biological effects of LPA, was inhibited by LPA in this study, and the regulation of p38 pathway by LPA was dependent on LPA ( 1/3 ) /Gi/ERK1/2 pathway mediated MKP-1 induction but independent of PI3K/Akt pathway
Cook et al., J Biol Chem 1997 : Inhibition of LPA stimulated MEK and ERK activation with PD98059 and pertussis toxin, a selective inhibitor of Gi-protein coupled signaling pathways, reduced LPA stimulated MKP-1 expression by only 50 %, suggesting the presence of additional MEK- and ERK independent pathways for MKP-1 expression